Opal Medical Study

On Tuesday 25/08/2026 I recieved some great news from taking part in the Opal Medical Study into weight loss. I had my pre screening on the 09/01/2026 at The Leicester General Hospital Diabetes Centre, an then had a Baseline taken on the 18/02/2026. After which I was randomised to the Mounjaro with Exercise arm of the study. At his point I was diabetic with type 2 Diabetes. I started tacking the Mounjaro on the 11/03/2026 and had an exercise session at the leicester General Hospital. From then the Mounjaro was gradually taken up from the minmum dose of 2.5mg to 10mg. at the twelve week review Ihad lost weight and gained muscle mass after going to the diabetes centre twice week when I was on earlies and whent to the Gym at Queens Park Leisure Centre twice a week when I was on lates.

The results from the twelve week review showed that I had gone back to prediabetes. After the twelve week review I was going to the Dibetes Centre once a week when I was on earlies and to Queens Park Gym one a week and twice a week on lates. I recorded all the gym sessions for the sports scientists and I started swimming again on Sundays too.

I went for my 24 week review on the 11/08/2026 at the diabetes centre and whent for my second muscle byopsy on the 17/08/2026 where I found out that I was in remission from diabetes. and my weight had fallen from 152kg to 135kg. On Tuesday 25/08/2026 I went to get my next Mounjaro quick pen and the doctor told me that I was free of Diabetes.

When I took my last 10mg dose on Wednesday my weight had gone down to 132.2kg.

While I have put in the had work to loose this weight and gain muscle I could not of done this without the doctors and sport scientists at the Dibetes Centre at Leicester General Hospital. I am now on the study 4B arm of the Opal Study and I still have to go to The Diabetes Centre once a month the get Mounjaro. I would like to say a big thank you to the doctors and sports scientists of the Leicester Diabetes Centre for all their help and input.

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